Lumefantrine

In chemistry, chemical synthesis is purposeful execution of chemical reactions in order to get a product, or several products. This happens by physical and chemical manipulations usually involving one or more reactions. In modern laboratory usage, this tends to imply that the process is reproducible, reliable, and established to work in multiple laboratories.

A chemical synthesis begins by selection of compounds that are known as reagents or reactants. Various reaction types can be applied to these to synthesize the product, or an intermediate product. This requires mixing the compounds in a reaction vessel such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of work-up procedure before the final product is isolated [1]. The amount of product in a chemical synthesis is the reaction yield. Typically, chemical yields are expressed as a weight in grams or as a percentage of the total theoretical quantity of product that could be produced. A side reaction is an unwanted chemical reaction taking place that diminishes the yield of the desired product.

We have been able to make a remarkable impression globally in our strengths to Supply the world class API's to regulated and non regulated markets. All our products are supported with EDMF's in CTD Format. We already have Certificate of Suitability for Simvastatin, Lovastatin and Propofol. We have already filed USDMF for our Simvastatin.

Aside from the hypotension (mainly through vasodilatation) and transient apnea following induction doses, one of propofol's most frequent side effects is pain on injection, especially in smaller veins. This pain can be mitigated by pretreatment with lidocaine.[6] Patients tend to show great variability in their response to propofol, at times showing profound sedation with small doses. A more serious but rare side effect is dystonia. Mild myoclonic movements are not uncommon, as with other intravenous hypnotic agents. Propofol appears to be safe for use in porphyria, and has not been known to trigger malignant hyperpyrexia.

Another recently described rare, but serious, side effect is propofol infusion syndrome. This potentially lethal metabolic derangement has been reported in critically-ill patients after a prolonged infusion of high-dose propofol in combination with catecholamines and/or corticosteroids.

Abuse of propofol as a recreational drug has been reported, usually among medical staff such as anaesthetists who have access to the drug. Despite a lack of analgesic properties, propofol's sedative action presumably produces euphoric effects. The steep dose response curve of the drug makes such abuse very dangerous without proper monitoring, and several deaths have been recorded.

A chemical synthesis begins by selection of compounds that are known as reagents or reactants. Various reaction types can be applied to these to synthesize the product, or an intermediate product. This requires mixing the compounds in a reaction vessel such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of work-up procedure before the final product is isolated [1]. The amount of product in a chemical synthesis is the reaction yield. Typically, chemical yields are expressed as a weight in grams or as a percentage of the total theoretical quantity of product that could be produced. A side reaction is an unwanted chemical reaction taking place that diminishes the yield of the desired product.

I start checking around, something I should have done earlier, and found that Accutane was available here by the same manufacturer (Roche) as in the USA and named Roaccutane. So, I get an American physician here to write a prescription and I take it to the Apollo Hospital pharmacy. The prescription is not even signed.