Orlistat (marketed as a prescription under the trade name Xenical by Roche or over-the-counter as Alli[2] by GlaxoSmithKline), also known as tetrahydrolipstatin, is a drug designed to treat obesity.[3] Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. It is intended for use in conjunction with a physician-supervised reduced-calorie diet