Sterile

To reduce the development of drug-resistant bacteria and maintain the effectiveness of MAXIPIME® and other antibacterial drugs, MAXIPIME should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

A third generation cephalosporin, cefoperazone sodium contains a piperazine side chain giving it antipseudomonal activity. It occurs as white, crystalline powder and is freely soluble in water and poorly soluble in alcohol. At room temperature, cefoperazone sodium has a maximum solubility in compatible IV solutions of 475 mg/ml (at concentrations >333 mg/ml vigorous and prolonged shaking may be required).

Causes severe irritation and burns. May Be harmful if swallowed. Avoid breathing vapor or dust. Use with adequate ventilation. Avoid contact with eyes, skin, and clothes. Wash thoroughly after handling. Keep container closed.

It is prescribed for infections of the lower respiratory tract, urinary tract, skin, abdomen, bones, and joints. It is also used to treat gonorrhea, septicemia, and meningitis and in surgical prophylaxis, particularly in coronary bypass operations. It has a comparatively long half-life and although its dosage must still be decreased with renal impairment, it is one of the few cephalosporins that is eliminated primarily by the liver.