Dimethyl sulfoxide (DMSO) is the chemical compound with the formula (CH3)2SO. It was first synthesized in 1866 by the Russian scientist Alexander Zaytsev, who reported his findings in a German chemistry journal in 1867.[1][2] This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water.